A Simple and Convenient Synthesis of Pseudoephedrine From N-Methylamphetamine

My favorite journal, Journal of Apocryphal Chemistry, has just published an interesting article.  The authors, O. Hai and I. B. Hakkenshit, describe a synthesis of pseudoephedrine from readily available crystal meth.  Pseudoephedrine is the decongestant in Sudafed, which used to be out on stores shelves.  Now if you want to buy it you have to show your drivers license at a pharmacy.  This synthesis should make it much easier to get this useful medicine.

 

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